News

Not only are our customers in the news - they make the news! We contribute to our customer's success with the very best science and technology that never stops advancing.  

Here we capture the more significant and interesting news stories we've been associated with along with our own.

22-11-17

Mass Spec to Present at IRC Showcase

The Innovative Research Call (IRC) for Explosives and Weapons Detection funded £3 million of innovative research projects to meet requirements for improved security and counter-terrorism.

Mass Spec Analytical will be presenting its IRC project Mobile QTOF trace detector with Low Temperature Plasma Ion Source at the THE INNOVATIVE RESEARCH CALL Funding Talks Programme – part of the UK Security Expo Exhibition and Conference held the 29th and 30th of November 2017.

This initiative was jointly funded by both UK Government and the United States of America Department for Homeland Security’s Science and Technology Directorate. Projects were awarded funding to support the development of supplier’s original ideas or adaptations of existing approaches from other sectors. Each project met the challenge of detecting explosives and weapons in one or more of the following scenarios: buildings and areas; goods; people and/or their possessions; and vehicles.

The IRC 2013 call has now concluded with a number of successful prototypes developed.

We are presenting the outcomes of our project and will be answering questions about how our findings can be further developed.

You can register for the exhibition and the Funding Talks Programme by following this link.

 

05-09-17

Sciex and Mass Spec Analytical Present High Resolution QTOF and SWATH Poster at BMSS Annual Meeting

Traditional security screening techniques can report erroneous responses when based solely upon collisional cross section measurements or differential mobility. A Sciex X500R QTOF coupled with a Mass Spec TEIS-3200 Ion source running SWATH software presents an alternative approach.

Sciex and Mass Spec have successfully integrated the X500R QTOF mass spectrometer with the TEIS-3200 ion source. As part of the test and validation process, the combination of a heated block based thermal desorption (TD) corona discharge ionization (CDI) source with an accurate mass Q-TOF mass spectrometer was tested for the analysis of dried explosive residues obtained from the swab of a surface. Traditional security screening techniques can report erroneous responses when based solely upon collisional cross section measurements or differential mobility.

In a poster that was presented at the BMSS Annual meeting in Manchester, September 2017, The potential application of a SWATH MS/MSALL acquisition for the direct analysis of dried explosive residues was reported.

Using nano-gram levels of known explosives spiked onto a flat surface that are presented to the ionisation source, both precursor and production ion information was generated in under 10 seconds. The SWATH MS/MSALL approach enables the analysis of accurate mass precursor ions enabling elemental composition and isotope pattern predictions and product ion data that are subsequently matched to MS/MS based libraries for enhanced identification confidence.

06-12-16

Mass Spec Demonstrates 100% Participant Screening at UK Security Expo

New Scentinel X500R can screen event-goers for all known explosives in seconds

Mass Spec Analytical demonstrated the Scentinel X500R as part of the Crowded Places Demonstrator at the UK Security Expo held at Olympia, London, November 30 – 1 December 2016. Designed for field and temporary deployments, Scentinel is a versatile trace detection system configured at the exhibition to demonstrate scanning 100% of admission tickets for explosives or other chemicals as part of the Crowded Places Demonstrator.

Detecting explosives or other chemical threats is a tremendous challenge for security personnel not wanting to disrupt the experience for the visiting public.  The Scentinel X500R addresses this challenge using a compact, portable system that is highly reliable and rigorous in its ability to detect explosive and other chemical threats quickly and with very few false alarms. Used for many years by security forces to secure high-security VIP events, this new evolution of Scentinel – the X500R - adds further detection capabilities and quicker more convenient operation making it a powerful robust detection strategy for public events.  

Dr. Richard Sleeman, Mass Spec Analytical Scientific Director explains: “The forensically acceptable results obtained from Scentinel provide laboratory-grade absolute accuracy in the field meaning that the rates of false positive and false negative are near to zero. The system is easy to use, reliable, uses few or no consumables and is so fast, it’s practical to test high quantities of samples in a continuous flow; like you see at large events or airport security stations. It’s also future-proof because it can be easily programmed to identify new threats (i.e., new substances) as they are identified.”

Scentinel’s technology is based on Mass Spec Analytical’s 20-years of extensive and proven techniques of analysis, developed in their UKAS ISO 17025-accredited laboratory.

 

05-07-16

Mass Spec Analytical Announces TEIS-3200 Thermal Extraction Ion Source

New rapid screening device reduces workflow times by 30% compared to chromatographic methods

Mass Spec Analytical announced today that its new Thermal Extraction Ion Source for the Sciex API 3200™Triple Quad System is now shipping to customers. The Mass Spec TEIS-3200 is ideal for applications where the method requires a large quantity of sample measurements in a relatively short period of time or where automation is required. When coupled with Mass Spec Analytical’s analysis software, results can be provided in as little as 4 seconds.

The TEIS-3200 uses Mass Spec's patented Thermal Extraction sample introduction device: two heated nickel coated brass plates with a cavity between them. Ambient air is continuously drawn into this space and through a ceramic transfer line into the Atmospheric Pressure Chemical Ionisation (APCI) ion source.  Compounds amenable to thermal desorption, such as many pesticides, drugs and explosives, can be rapidly analysed in this way without the need for any sample pre-treatment, solvents or glassware. The approach of directly analysing materials by thermal desorption tandem mass spectrometry (TD-MSMS) has been successfully applied to the forensic analysis of drugs of abuse, the detection of explosives, and with reference to an increasing database of MS/MS spectra, could help to identify an expanding suite of compounds.

Dr. Richard Sleeman, Mass Spec Analytical Scientific Director explains: “The TEIS-3200 is easy to use, reliable, uses few or no consumables and is very fast. The thermal system liberates samples from a large surface area, and so is ideal as a rapid screening method. Coupled with the specificity afforded by a Sciex API 3200™Triple Quad, the overall system is able to provide real-time results to a forensic standard.”

The Thermal Extraction Ion Source significantly speeds up workflow times by 30% or more for processes where GCMS is normally used for analysis. Much of the time saved is in the sample queue for analysis, which may be overnight, but there are other savings: no solvents, no glassware, no labelling of vials, no loading up the auto-sampler, no reconciling the queue with the sample list, no reconciling the results to the correct vial in the correct position, no GC columns, no special gases.  An added benefit is that the lab would be in a position to give virtually instantaneous results to their clients or colleagues once the analysis is complete.

The analytical system has been peer reviewed by academics and government agencies. Contact Mass Spec Analytical for further references and more information. The TEIS-3200 is available to order now.

 

For research use only. Not for use in diagnostic procedures.

07-06-16

Border Security with Accuracy, Reliability, and Reproducibility

Sciex Blog reports reviews a recent paper in the Journal of Forensic Science1, a comprehensive evaluation using Mass Spectrometry for the trace detection of 2,4,6-trinitrotoluene, C-4, Semtex-H, Datasheet, and HMTD.

The  global company, SCIEX, leaders in the liquid chromatography-mass spectrometry industry has recently written about the work reviewed in a recent paper from scientists working at the Canadian Border Security Agency (CBSA). They noted the importance of protecting a country’s border from the war on drugs and terror is a 24/7 task 366 days a year (2016 is a leap year).  Sciex noted that Mass Spectrometry is rapidly becoming the instrument of choice for border agencies throughout the world when it comes to explosive trace detection and forensic drug compounds.

The technology employed in this study was a SCIEX API 3200™ System Mass Spectrometer configured as a Mass Spec Scentinel system: a thermal desorption and atmospheric pressure chemical ionization (APCI) source  The unique feature of this technique is that it is a chromatography-free analytical solution. There is no need for intensive sample prep or LC gradient, the sample is introduced to the source and produces a response in a very short period. The findings of this evaluation concluded that,“The direct analysis by mass spectrometry using the Scentinel transformed the traditional day-long quantification analysis of solvent extraction chromatography to minutes, eliminated sample loss, and allowed the transfer efficiency to be quantified for every test surface used.”

The Canadian Border Service Agency (CBSA) requirement for testing explosives detectors is just one such application that could be carried out using this configuration.