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Mass Spec has spent hundreds of man years developing the finest mass spectrometry testing hardware and introduction sampling systems available.

Now you can acquire this expertise for your own laboratory.

C-TEIS for Waters RADIAN

C-TEIS is an exciting all-new thermal source for the Waters RADIAN: a novel, dedicated direct analysis system specifically designed for rapid, easy, and low-cost analysis of liquids and solids. Engineered using proven and robust single quadrupole mass spectrometry technology, it’s purpose is to bring mass spectrometry to mass applications. RADIAN delivers quality and ease of use in a compact footprint.

The RADIAN™ single quadrupole mass detector provides high quality mass spectral data, without the need for any special training or expertise thus eliminating any need to contract out and wait for results from specialist analytical service laboratories. Mass Spec Analytical has been working with Waters for several years developing thermal sources, first for the QDa, and later, for the RADIAN instruments. The objective was to demonstrate that a new approach to desktop, easily transported, trace detection instrumentation can work across a wide range of compound groups using a traditional sampling technique. Detection at low nanogram ranges for a sample has been demonstrated on development prototypes. Initial applications demonstrated include detection of explosives, drugs, pesticides, and industrial chemicals.  

The C-TEIS is a Compact Thermal Extraction Ion Source manufactured from composite materials and utilises new volatilisation heater technology. The MSA C-TEIS interchanges with the Atmospheric Solids Analysis Probe (ASAP)[1] supplied by Waters with the instrument. Both sources rely on Atmospheric pressure chemical ionization (APCI) as an ionisation method that utilizes gas-phase ion-molecule reactions at atmospheric pressure. The C-TEIS is fully integrated with the RADIAN with all source power and operational controls provided by the instrument.

[1] As a rule of thumb, the ASAP approach is more suited to bulk samples (those which are visible to the naked eye), whereas the swabbing approach is more suited to trace analysis (samples which cannot be seen).  


The C-TEIS is optimised for trace detection from sampling materials up to 50mm wide. RADIAN features the ability to use different cone voltages to bring about differing degrees of in-source fragmentation. This innovation significantly increases the specificity achieved, enabling the C-TEIS to compete with Ion Mobility Spectrometers in terms of cost, whilst significantly outperforming them in terms of analytical precision. 

The C-TEIS source is scheduled to be available from Q3 2024. 

Download the Product Sheet for C-TEIS here.

Contact MSA if you would like to know more or have an application you would like to discuss.

RADIAN is a registered trademarks of Waters Instrument Corporation

Contact Mass Spec Analytical on  +44(0)117 428 5787