Mass Spec Analytical presented its latest Scentinel application software at a recent British Mass Spectrometry Society event. Produced in conjunction with our partners SpectralWorks Limited, the application takes the comprehensive analysis from a triple-quadrupole mass spectrometer instrument and reduces it to a simple Yes/No result. The operator gets instant feedback and expert users can review results, either on-site or remotely.

All data is archived and easily retrieved for data mining or trend analysis. The software can be adapted to a range of other applications including drug identification.

The poster presented at the event is available here.

Sciex and Mass Spec have successfully integrated the X500R QTOF mass spectrometer with the TEIS-3200 ion source. As part of the test and validation process, the combination of a heated block based thermal desorption (TD) corona discharge ionization (CDI) source with an accurate mass Q-TOF mass spectrometer was tested for the analysis of dried explosive residues obtained from the swab of a surface. Traditional security screening techniques can report erroneous responses when based solely upon collisional cross section measurements or differential mobility.

In a poster that was presented at the BMSS Annual meeting in Manchester, September 2017, The potential application of a SWATH MS/MS^ALL acquisition for the direct analysis of dried explosive residues was reported.

Using nano-gram levels of known explosives spiked onto a flat surface that are presented to the ionisation source, both precursor and production ion information was generated in under 10 seconds. The SWATH MS/MS^ALL approach enables the analysis of accurate mass precursor ions enabling elemental composition and isotope pattern predictions and product ion data that are subsequently matched to MS/MS based libraries for enhanced identification confidence.